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MDCK-MRP2 - Dkfz

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118<br />

Forschungsschwerpunkt B<br />

Funktionelle und Strukturelle Genomforschung<br />

[6] F. Bestvater, T.A. Knoch, J. Langowski, E. Spiess: GFP-Walking:<br />

Artificial construct conversions caused by simultaneous<br />

cotransfection. (2002) BioTechniques 32(4), 844-55<br />

[7] Dekker, J.*, Rippe, K., Dekker, M.* & Kleckner, N.* (2002).<br />

Capturing Chromosome Conformation. Science 295(5558), 1306-<br />

1311.<br />

[8] I. Hofmann, H. Winter, N. Mücke, J. Langowski, J. Schweizer:<br />

The in vitro assembly of hair follicle keratins: Comparision of cortex<br />

and companion layer keratins. (2002) Biol. Chem. 383(9),<br />

1373-81<br />

[9] M. Gumbel, R. Grebe, M. Knapp-Mohammady, G. M.<br />

Ullmann*, J. Langowski: Modellierung biologischer Prozesse. In:<br />

Handbuch der Medizinischen Informatik (T. Lehmann & E. Meyer<br />

zu Bexten, eds.) Hanser, München 2002.<br />

[10] *Gil-Parrado, S., *Fernandez-Montalvan, A., *Assfalg-<br />

Machleidt, I., *Popp, O., Bestvater, F., *Holloschi, A., Knoch, T.<br />

A., *Auerswald, E. A., *Welsh, K., Reed, J. C., *Fritz, H.,<br />

*Fuentes-Prior, P., Spiess, E., *Salvesen, G. S. & *Machleidt, W.<br />

(2002). Ionomycin-activated calpain triggers apoptosis: A probable<br />

role for Bcl- 2 family members. J Biol Chem 8, 8.<br />

[11] G. Westphal*, S. van den Berg-Stein*, K. Braun, T.A.<br />

Knoch, M. Dümmerling*, J. Langowski, J. Debus, E. Friedrich*:<br />

Detection of the NGF receptors TrkaA and p75NTR and effect of<br />

NGF on the growth characteristics of human tumor cell lines.<br />

(2002) J. Exp. Clin. Cancer Res., 21(2), 255-67<br />

[12] K. Braun, P. Peschke, R. Pipkorn, S. Lampel*, M.<br />

Wachsmuth, W. Waldeck, E. Friedrich*, J. Debus: A biological<br />

transporter for the delivery of peptide nucleic acids (PNAs) to<br />

the nuclear compartment of living cells. (2002) J. Mol. Biol.,<br />

318(2):237-43<br />

[13] Strunz AM, Peschke P, Waldeck W, *Ehemann V, Kissel M,<br />

Debus J.: Preferential radiosensitization in p53-mutated human<br />

tumour cell lines by pentoxifylline-mediated disruption of the G2/<br />

M checkpoint control. (2002) Int J Radiat Biol. 78(8):721-32<br />

[14] M. Wachsmuth, T. Weidemann, G. Müller, W. Waldeck, J.<br />

Langowski: Analyzing intracellular binding and diffusion with continuous<br />

fluorescence photobleaching. (2003) Biophys. J. 84,<br />

3353-3363<br />

[15] T.P. O’Brien*, C. Cremer*, M. Grunze*, B.B. Knowles*, J.<br />

Langowski, J. McNally*, T. Pederson*, J. Politz*, A. Pombo*, P.<br />

Schmidt*, R. van Driel*: Functional Architecture of the Nuclear<br />

Genome: Towards establishing the Genome Architecture Consortium.<br />

(2003) Genome Res. 13, 1029-1041<br />

[16] K. Módos*, R. Galántai*, I. Bardos-Nagy*, M. Wachsmuth,<br />

K. Tóth, J. Fidy*, J. Langowski: Maximum-entropy decomposition<br />

of fluorescence correlation spectroscopy data: application to liposome-human<br />

serum albumin association. (2003) Eur. Biophys.<br />

J., published online 30.08.2003, DOI: 10.1007/s00249-003-<br />

0343-6<br />

[17] F. Lankaš, J. Šponer*, J. Langowski, T.E. Cheatham III*:<br />

DNA base-pair step deformability inferred from molecular dynamics<br />

simulations. (2003) Biophys. J., 85(5), 2872-2883<br />

[18] J. F. Kepert*, K. Fejes Tóth*, M. Caudron*, N. Mücke, J.<br />

Langowski, K. Rippe: Conformation of reconstituted mononucleosomes<br />

determined by scanning force microscopy in air and in<br />

aqueous solution. (2003) Biophys. J., 85(6), 4012-22<br />

[19] T. Weidemann, M. Wachsmuth, T.A. Knoch, G. Müller, W.<br />

Waldeck, J. Langowski; Counting nucleosomes in living cells with<br />

a combination of fluorescence correlation spectroscopy and confocal<br />

imaging. (2003) J. Mol. Biol. 334(2), 229-240.<br />

[20] M. Bussiek, N. Mücke, J. Langowski: Polylysine-coated mica<br />

can be used to observe systematic changes in the supercoiled<br />

DNA conformation by scanning force microscopy in solution.<br />

(2003) Nucl. Acids Res., 31(22), e137<br />

[21] M. Egyeki, G. Turoczy*, Z. Majer*, K. Tóth, A. Fekete*, P.<br />

Maillard*, G. Csik*: Photosensitized inactivation of T7 phage as<br />

surrogate of non-enveloped DNA viruses: efficiency and mechanism<br />

of action. (2003) Biochim Biophys Acta 1624, 115-24<br />

Abteilung B040<br />

Biophysik der Makromoleküle<br />

DKFZ 2004: Wissenschaftlicher Ergebnisbericht 2002 - 2003<br />

[22] M. Egyeki, G. Turoczy*, K. Tóth, A. Fekete*, P. Maillard*,<br />

G. Csik*: Photodynamic inactivation of porphyrin sensitized T7<br />

phages: efficiency and mechanism of action. (2003) Acta Pharm<br />

Hung 73(2): 97-102.<br />

[23] S. Heckl, R. Pipkorn, W. Waldeck, H. Spring, J. Jenne, C.-<br />

W. von der Lieth, H. Corban-Wilhelm, J. Debus, K. Braun. Intracellular<br />

Visualization of Prostate Cancer using Magnetic Resonance<br />

Imaging. (2003) Cancer Res. 63, 4766-72<br />

[24] *Gil-Parrado, S., *Popp, O., Knoch, T. A., Zahler, S.,<br />

Bestvater, F., Felgentrager, M., *Holloschi, A., *Fernandez-<br />

Montalvan, A., *Auerswald, E. A., *Fritz, H., *Fuentes-Prior, P.,<br />

*Machleidt, W. & Spiess, E.: Subcellular localization and in vivo<br />

subunit interactions of ubiquitous mu-calpain (2003) J Biol Chem<br />

278, 16336-46.<br />

[25] Braun, K., Wolber, G., Waldeck, W., Pipkorn, R., Jenne, J.,<br />

Rastert, R., *Ehemann, V., Eisenmenger, A., Corban-Wilhelm, H.,<br />

Braun, I., Heckl, S. & Debus, J.: The enhancement of neutron<br />

irradiation of HeLa-S cervix carcinoma cells by cell-nucleus-addressed<br />

deca-p-boronophenylalanine. (2003) Eur J Med Chem<br />

38, 587-95.<br />

[26] Perraud, A. L.*, Shen, B.*, Dunn, C. A.*, Rippe, K., Smith,<br />

M. K.*, Bessman, M. J.*, Stoddard, B. L.* & Scharenberg, A.<br />

M.*: NUDT9, a member of the Nudix hydrolase family, is an evolutionarily<br />

conserved mitochondrial ADP-ribose pyrophosphatase.<br />

(2003) J Biol Chem 278, 1794-801.<br />

[27] N. Mücke, L. Kreplak*, R. Kirmse, T. Wedig, H. Herrmann,<br />

U. Aebi*, J. Langowski: Assessing the Flexibility of Intermediate<br />

Filaments by Atomic Force Microscopy. (2004) J. Mol. Biol.<br />

335(5), 1241-1250<br />

[28] J. Langowski, H. Schiessel*: Theory and computational<br />

modeling of the 30 nm chromatin fiber. In: Chromatin Structure:<br />

State of the Art, eds. S. Leuba & J. Zlatanova, 2004, Elsevier,<br />

Amsterdam.<br />

[29] J. Langowski: Melting Under Stress (New and Notable Comment<br />

on article “Monte Carlo Simulations of Locally Melted Supercoiled<br />

DNAs in 20mM Ionic Strength” by Sucato et al. in the same<br />

journal). (2004) Biophys. J., in press<br />

[30] F. Lankaš, J. Šponer*, J. Langowski, T.E. Cheatham III*:<br />

DNA deformability at the base-pair level. (2004) J. Am. Chem.<br />

Soc.,126(13) 4124-4125<br />

[31] N. Mücke, T. Wedig, A. Bürer*, L. N. Marekov*, P. M.<br />

Steinert*, J. Langowski, U. Aebi*, H. Herrmann: Molecular and<br />

Biophysical Properties of Assembly-Starter-Units of Human<br />

Vimentin. (2004) J. Mol. Biol., in press

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