MDCK-MRP2 - Dkfz

Forschungsschwerpunkt E
Innovative Krebsdiagnostik und -therapie
[25] Abdollahi A., Lipson K.E., Sckell A., Zieher H., Klenke F.,
Poerschke D., Roth A., Han X., Krix M., Bischof M., Hahnfeldt P.,
Gröne H.-J., Debus J., Hlatky L., Huber P.E.; Combined therapy
with direct and indirect angiogenesis inhibition results in enhanced
anti-angiogenic and anti-tumor effects Cancer Research
15: 8890-8898, 2003
[26] *Anders H.J., *Banas B., *Linde Y., *Weller L., *Cohen C.D.
*Kretzler M., *Martin S., *Vielhauer V., *Schlöndorff D., Gröne
H.-J.: Bacterial CpG-DNA aggravates Immune Complex Glomerulonephritis.
Role of TLR9-mediated Expression of Chemokines
and Chemokine Receptors. J. Am. Soc. Nephrol. 14: 317-326,
2003
[27] *Anders H.J., *Frink M, *Linde Y., *Banas B., *Wörnle M.,
*Cohen C.D., *Vielhauer V., *Nelson P.J., Gröne H.-J.,
*Schlöndorff D.: CC Chemokine Ligand 5/RANTES Chemokine Antagonists
aggravate Glomerulonephritis despite reduction of
Glomerular Leukocyte Infiltration. J. Immunol. 170: 5658-5666,
2003
[28] *Bennion B., *Park C., *Fuller M., *Lindsey R., *Momany M.,
Jennemann R., *Levery S.B.: Glycosphingolipids of the model
fungus Aspergillus nidulans: characterization of CIPCs with oligo-
(alpha)-mannose-type glycans. J. Lipid Res. 44: 2073-2088,
2003
[29] Del Barco Barrantes I., Davidson G, Gröne H.-J., Westphal
H., Niehrs C.: Dkk1 and noggin cooperate in mammalian head induction.
Genes Dev. 17: 2239-2244, 2003
[30] *Eitner F, *Ostendorf T., *Kretzler M., *Cohen C.D.,
*Eriksson U, Gröne H.-J., *Floege J.: PDGF-C Expression in the
Developing and normal adult human kidney and in glomerular diseases.
J. Am. Soc. Nephrol 14: 1145-53, 2003
[31] *Floege J., Gröne H.-J. IgA-Nephropathie häufig, jedoch nur
selten diagnostiziert Internist 44: 131-1139, 2003
[32] *Hepbildikler S.T., Wendeler M., Sandhoff R., *Sandhoff K.
Interaction of the GM2 activator protein with sulfated and
sialylated glycosphingolipids. Methods Enyzmol. 363: 207-222,
2003
[33] Hergenhahn M., Kenzelmann M., Gröne H.-J.: Laser-controlled
microdissection of tissues opens a window of new opportunities
Pathol Res Pract. 199: 419-423, 2003
[34] Herrmann T., van der Hoeven F., Gröne H.-J., Stewart A.F.,
Langbein L., Kaiser I., Liebisch G., Gosch, I., Buchkremer F.,
Drobnik W., Schmitz G., Stremmel W.: Mice with targeted disruption
of the fatty acid transport protein 4 (Fatp4, Slc27a4) gene
show features of lethal restrictive dermopathy. J. Cell Biol. 161:
1-13, 2003
[35] Herrmann T., Muckenthaler M., van der Hoeven F., Brennan
K., Gehrke SG., Hubert N., Sergi C., Gröne H.-J., Kaiser I., Gosch
I., Volkmann M., Riedel H.D., Hentze M.W., Stewart A.F.,
Stremmel, W.: Iron overload in adult Hfe-deficient mice independent
of changes in the steady-state expression of the duodenal
iron transporters DMT1 and Ireg1/ferroportin. J Mol Med. 82: 39-
48, 2004
[36] Kiss E., *Adams J., Gröne H.-J., *Wagner J.: Isotretinoin
ameliorates renal damage in experimental acute renal allograft
rejection. Transplantation 76: 480-489, 2003
[37] *Komhoff M., *Reinalter S.C., Gröne H.-J., Seyberth H.W. ;
Induction of Microsomal Prostaglandin E2 Synthase in the Macula
Densa in Children with Hypokalemic Salt-Losing Tubulopathies.
Pediatr Res. 55: 261-266, 2004
[38] Kunter U., *Floege J., von Jürgensonn A.S., Stojanovic T.,
Merkel S., Gröne H.-J., Ferran C.: Expression of A20 in the Vessel
Wall of Rat Kidney Allografts Correlates with Protection from
Transplant Arteriosclerosis. Transplantation 75: 3-9, 2003
[39] Lenz T., Haak T., Malek J., Gröne H.-J., Geiger H., Gossmann
J.: Vascular endothelial growth factor in diabetic nephropathy.
Kidney Blood Press Res. 26:338-343, 2003
[40] *Malle E., Buch T., Gröne H.-J.: Myeloperoxidase in kidney
disease Kidney Int. 64: 1956-1967, 2003
Abteilung E090
Zelluläre und Molekulare Pathologie
[41] Muhlbauer K.R., Gröne H.-J., Ernst T., Gröne E.F., Tschada
R., Hergenhahn M., Hollstein M.: Analysis of human prostate
cancers and cell lines for mutations in the TP53 and KLF6 tumor
suppressor genes British J. Cancer 89: 687-690, 2003
[42] Peitsch W.K., Hofmann I., Endlich N., Pratzel S., Kuhn C.,
Spring H., Gröne H.-J., Kriz W., Franke W.W.: Cell biological and
biochemical characterization of drebrin complexes in mesangial
cells and podocytes of renal glomeruli. J. Am. Soc. Nephrol. 14:,
1452-1463, 2003
[43] *Rookmaaker M.B., *Smits A.M., *Tolboom H., *van ‘t Wout
K., *Martens A.C., *Goldschmeding R., *Joles J.A., *van
Zonneveld A.J., Gröne H.-J., *Rabelink T.J., *Verhaar M.C.:
Bone-marrow-derived cells contribute to glomerular endothelial
repair in experimental glomerulonephritis. Am. J. Pathol. 163:
553-562, 2003
[44] *Schaier M., *Jocks,T., Gröne H.-J., *Ritz E., *Wagner J.:
Retinoid agonist isotretinoin ameliorates obstructive renal injury
J. Urology 170: 1398-1402, 2003
[45] Schmid H., Henger A., *Cohen C.D., Frach K., Gröne H.-J.,
*Schlöndorff D., *Kretzler M.: Gene expression profiles of
podocyte-associated molecules as diagnostic markers in acquired
proteinuric diseases. J. Am. Soc. Nephrol. 14: 2958-2966, 2003
[46] *Yamashita T., *Hashiramoto A., *Haluzik M., *Mizukami H.,
*Beck S., *Norten A., *Kono M., *Tsuji S., *Daniotti J.L., *Werth
N., Sandhoff R., *Sandhoff K., *Proia R.L. Enhanced insulin sensitivity
in mice lacking ganglioside Gm3 Proc Natl. Acad Sci USA
18: 3445-3449, 2003
[47] *Henger A., *Kretzler M., *Doran P., Bonrouhi M., Schmid H.,
Kiss E., *Cohen C.D., Madden S., Porubsky S., Gröne E.F.,
*Schlöndorff D., *Nelson P.J., Gröne H.-J.: Gene Expression fingerprints
in human tubulointerstitial inflammation and fibrosis as
prognostic markers of disease progression Kidney Int. 65: 904-
17, 2004
[48] *Anders H.J., Vielhauer V., Linde Y., Ketzler M., Perez de
Lema G., Strutz F., Bauer S., Rutz M., Wagner H., Gröne H.-J.,
*Schlöndorff D. Activation of Toll-like receptor-9 induces progression
of MRL-Fas (lpr) mice FASEB J. 18: 534-536, 2004
[49] Eis V., Vielhauer V., Siveke J., Linde Y., Segerer S., Perez de
Lema G., *Cohen C.D., *Kretzler M., Mack M., Horuk R., Murphy
P.M., Gao J.L. Hudkins K.L., Alpers C.E., Gröne H.-J.,
*Schlöndorff D., *Anders H.J.: Chemokine Receptor CCR1 but
not CCR5 mediates leukocyte recruitment and subsequent renal
fibrosis after unilaterial ureteral obstruction. J. Am. Soc Nephol.
15: 337-347, 2004
[50] Segerer S., Banas B., Wörnle M., Schmid H., *Cohen C.D.,
*Kretzler M. Mack M., *Nelson P.J., *Schlöndorff D., Gröne H.-J.:
CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis
Am J.. Pathol. 164: 635-649, 2004
DKFZ 2004: Wissenschaftlicher Ergebnisbericht 2002 - 2003
343