MDCK-MRP2 - Dkfz

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Forschungsschwerpunkt D
Tumorimmunologie
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J.A. Rotolo*, J. Ongchin*, L.M. Willis*, A.S. Greenberg*, J.M.
Eng*, J.M. Crawford*, G.F. Murphy*, H. Yagita*, H. Walczak,
J.J. Peschon*, and M.R. van den Brink*, T cells require TRAIL
for optimal graft-versus-tumor activity. Nat Med, 2002. 8(12): p.
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[7] Sträter*, J., H. Walczak, T. Pukrop*, L. Von Müller*, C.
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[8] Sträter, J.*, U. Hinz*, H. Walczak, G. Mechtersheimer*, K.
Koretz*, C. Herfarth*, P. Möller*, and T. Lehnert*, Expression of
TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an
independent prognostic parameter. Clin Cancer Res, 2002.
8(12): p. 3734-40.
[9] Hasel, C.*, S. Dürr*, B. Rau*, J. Sträter*, R.M. Schmid*, H.
Walczak, M.G. Bachem*, and P. Möller*, In chronic pancreatitis,
widespread emergence of TRAIL receptors in epithelia coincides
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[10] Dörr, J.*, I. Bechmann*, S. Waiczies*, O. Aktas*, H.
Walczak, P.H. Krammer, R. Nitsch*, and F. Zipp*, Lack of tumor
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its receptors in the human brain. J Neurosci, 2002. 22(4): p.
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[11] Sprick, M.R. and H. Walczak, The interplay between the Bcl-
2 family and death receptor-mediated apoptosis. Biochim Biophys
Acta, 2004 1644(2-3): 125-132.
[12] Ganten, T.M., T.L. Haas, J. Sykora, H. Stahl, M.R. Sprick,
S.C. Fas, A. Krueger, M.A. Weigand, A. Grosse-Wilde, W.
Stremmel*, P.H. Krammer, and H. Walczak, Enhanced Caspase-8
Recruitment to and activation at the DISC is Critical for
Sensitisation of Human Hepatocellular Carcinoma cells to TRAILinduced
Apoptosis by Chemotherapeutic Drugs. Cell Death Diff.
In press.
D040
Apoptose Regulation
DKFZ 2004: Wissenschaftlicher Ergebnisbericht 2002 - 2003