MDCK-MRP2 - Dkfz
MDCK-MRP2 - Dkfz
MDCK-MRP2 - Dkfz
Erfolgreiche ePaper selbst erstellen
Machen Sie aus Ihren PDF Publikationen ein blätterbares Flipbook mit unserer einzigartigen Google optimierten e-Paper Software.
214<br />
Forschungsschwerpunkt C<br />
Krebsrisikofaktoren und Krebsprävention<br />
[68] Korz C., Pscherer A., Benner A., Mertens D., Schaffner<br />
C., Leupolt E., Döhner H., Stilgenbauer S., Lichter P.: Evidence<br />
for distinct pathomechanisms in B-cell chronic lymphocytic leukemia<br />
and mantle cell lymphoma by quantitative expression analysis<br />
of cell cycle and apoptosis-associated genes. Blood 99 (12)<br />
4554-4561, 2002.<br />
[69] Kröber A., Seiler T., Benner A., Bullinger L., Brückle E.,<br />
Lichter P., Döhner H., Stilgenbauer S.: V(H) mutation status,<br />
CD38 expression level, genomic aberrations, and survival in<br />
chronic lymphocytic leukemia. Blood 100 (4) 1410-1416, 2002.<br />
[70] Kuntz C., Kienle P., Schmeding M., Benner A., Autschbach<br />
F., Schwalbach P.: Comparison of laparoscopic versus conventional<br />
technique in colonic and liver resection in a tumor-bearing<br />
small animal model. Surg.Endosc. 16 (8) 1175-1181, 2002.<br />
[71] Laack E., Mende T., Dürk H., Kneba M., Dickgreber N.,<br />
Welte T., Müller T., Scholtze J., Graeven U., Jasiewicz Y., Edler<br />
L., Hossfeld D.K.: Gemcitabine, vinorelbine and cisplatin combination<br />
chemotherapy in advanced non-small cell lung cancer: a<br />
phase II trial. Europ.J.Cancer 38 654-660, 2002.<br />
[72] Laack E., Nikbakht H., Peters A., Kugler C., Jasiewicz Y.,<br />
Edler L., Brümmer J., Schumacher U., Hossfeld D.K.: Expression<br />
of CEACAM1 in adenocarcinoma of the lung: a factor of independent<br />
prognostic significance. J.Clin.Oncol. 20 (21) 4279-4284,<br />
2002.<br />
[73] Laack E., Nikbakht H., Peters A., Kugler C., Jasiewicz Y.,<br />
Edler L., Hossfeld D.K., Schumacher U.: Lectin histochemistry of<br />
resected adenocarcinoma of the lung. Helix pomatia agglutinin<br />
binding is an independent prognostic factor. Am.J.Pathol. 160 (3)<br />
1001-1008, 2002.<br />
[74] Laufs S., Gentner B., Nagy K.Z., Jauch A., Benner A.,<br />
Naundorf S., Kühlcke K., Schiedlmeier B., Ho A.D., Zeller W.J.,<br />
Frühauf S.: Retroviral vector integration occurs into preferred<br />
genomic targets of human bone marrow repopulating cells. Blood<br />
101 (6) 2191-2198, 2003.<br />
[75] Leupolt E., Stilgenbauer S., Kröber A., Benner A., Lichter<br />
P., Döhner H.: Clonal evolution in B-CLL-association with IgVH homology,<br />
disease progression and in-vivo resistance to therapy.<br />
Onkol. 25(S4), p.172 (608), 2002.<br />
[76] Liebisch P., Erne S., Scheck D., Wellmann A., Einsele H.,<br />
Straka C., Goldschmidt H., Benner A., Stilgenbauer S., Döhner<br />
H.: In multiple myeloma, five common genomic aberrations (+1q,<br />
+9q, +11q, 13q-, t14q) display a non-random distribution and<br />
suggest novel pathogenetic pathways. Onkol. 26(S5), p.121<br />
(P684), 2003.<br />
[77] Liebisch P., Wellmann A., Wendl C., Roth K., Benner A.,<br />
Stilgenbauer S., Döhner H.: Trisomies of chromosomes 1q, 9q,<br />
and 11q in multiple myeloma - non-random distribution of three<br />
highly frequent aberrations. Onkol. 25(S4), pp.73-74 (252),<br />
2002.<br />
[78] Lutz W.K., Vamvakas S., Kopp-Schneider A., Schlatter J.,<br />
Stopper H.: Deviation from additivity in mixture toxicity: relevance<br />
of nonlinear dose-response relationships and cell line differences<br />
in genotoxicity assays with combinations of chemical<br />
mutagens and y-radiation. Environ.Hlth.Persp. 110 (Suppl.6)<br />
915-918, 2002.<br />
[79] Manegold C., Mezger J., Pilz L.R., Schott K., Koschel G.,<br />
Hruska D.: Single-agent gemcitabine and docetaxel given sequentially<br />
every 3 weeks in advanced NSCLC: final results of a<br />
randomized phase-II-study show effective treatment. Onkol.<br />
26(S5), p.140 (P753), 2003.<br />
[80] Manegold C., Pilz L., Koschel G., Schott K., Hruska D.,<br />
Mezger J.: Final results from two randomized phase II studies<br />
with single agent gemcitabine and docetaxel given sequentially in<br />
various doses and schedules are effective in advanced NSCLC.<br />
Proc.ASCO (No.1273), 2002.<br />
[81] Manegold C., Pilz L., Koschel G., Schott K., Hruska D.,<br />
Mezger J.: Survival data from two randomized phase II studies<br />
show effectiveness for therapy of advanced NSCLC by single<br />
agent gemcitabine and docetaxel given sequentially in various<br />
doses and schedules. J.Cancer Res.Clin.Oncol. 128(Suppl.1),<br />
p.74 (P376), 2002.<br />
C060<br />
Biostatistik<br />
DKFZ 2004: Wissenschaftlicher Ergebnisbericht 2002 - 2003<br />
[82] Markowetz F., Edler L., Vingron M.: Support vector machines<br />
for protein fold class prediction. Biometr.J. 45 (3) 377-<br />
389, 2003.<br />
[83] Möhler T., Hillengass J., Höpfner S., Benner A., Schlenzka<br />
J., Neben K., Egerer G., Görner M., Ho A.D., Goldschmidt H.:<br />
Thalidomide and CED chemotherapy followed by stem cell transplantation<br />
for poor prognosis multiple myeloma. Onkol. 26(S5),<br />
p.132 (P720), 2003.<br />
[84] Müller A., Drings P., Rittgen W., Manegold C.: CNS-relapse<br />
after multimodality treatment of stage III non-small cell<br />
lung cancer. J.Cancer Res.Clin.Oncol. 128(Suppl.1), p.76<br />
(P384), 2002.<br />
[85] Neben K., Korshunov A., Benner A., Wrobel G., Hahn M.,<br />
Golanov A., Lichter P.: Identification of novel prognostic markers<br />
in medulloblastoma by gene expression experiments. Onkol.<br />
26(S5), p.37 (V352), 2003.<br />
[86] Neben K., Korshunov A., Wrobel G., Tews B., Benner A.,<br />
Hahn M., Golanov A., Lichter P.: Gene expression patterns in<br />
ependymoma correlate with tumor location and patient age.<br />
Onkol. 26(S5), p.203 (P981), 2003.<br />
[87] Oberemm A., Querfurth N., Dieterich A., Meckert C.,<br />
Brandenburger L., Herzig A., Lindner Y., Krause E., Ittrich C.,<br />
Kopp-Schneider A., Richter-Reichhelm H.B., Gundert-Remy U.:<br />
Proteomic analysis of TCDD-mediated effects in marmoset liver<br />
and thymus. Naunyn-Schmiedeb.Arch.Pharmacol. 367(Suppl.1),<br />
p.R153 (599), 2003.<br />
[88] Oberemm A., Querfurth N., Meckert C., Brandenburger L.,<br />
Herzig A., Kalenberg K., Krause E., Ittrich C., Kopp-Schneider<br />
A., Hellmann J., Bannasch P., Richter-Reichhelm H.B., Gundert-<br />
Remy U.: Proteomic investigation into n-nitrosomorpholine mediated<br />
changes in rat liver. Toxicol.Lett. 144(Suppl.1), p.s103<br />
(379), 2003.<br />
[89] Öhm C., Ittrich C., Mezger J., Langenbuch T., Eckardt<br />
M.J., Lehban H., Rehm M., Schulz G., Seipelt G., Ehlert T., Stauch<br />
M., Wolters U., Edler L.: Gemcitabine and vindesin combination<br />
regimen in inoperable metastatic non-small cell lung cancer: a<br />
phase II study. Onkol. 26(S5), p.141 (P754), 2003.<br />
[90] Pauli T., Pilz L., Rittgen W.: A stochastic model of the<br />
human skin under consideration of cell proliferation and differentiation<br />
and its realization as a simulation model.<br />
Inf.Biom.Epidem.Med.Biol. 34(3), pp.309-311, 2003.<br />
[91] Renwick A.G., Barlow S.M., Hertz-Piccioto I., Boobis A.R.,<br />
Dybing E., Edler L., Eisenbrand G., Greig J.B., Kleiner J., Lambe<br />
J., Müller D.J.G., Smith M.R., Tritscher A., Tuijtelaars S., van den<br />
Brandt P., Walker R., Kroes R.: Risk characterization of chemicals<br />
in food and diet. Final part of Food Safety in Europe (FOSIE):<br />
Risk assessment of chemicals in food and diet (EC concerted action<br />
QLK1-1999-00156). Food Chem.Toxicol. 41 (9 special issue)<br />
1211-1271, 2003.<br />
[92] Salowsky R., Heiss N.S., Benner A., Wittig R., Poustka A.:<br />
Basal transcription activity of the dyskeratosis congenita gene is<br />
mediated by Sp1 and Sp3 and a patient mutation in a Sp1 binding<br />
site is associated with decreased promoter activity. Gene 293 (1-<br />
2) 9-19, 2002.<br />
[93] Schlenk R.F., Benner A., Hartmann F., del Valle F., Weber<br />
C., Pralle H., Fischer J., Gunzer U., Pezzutto A., Weber W.,<br />
Grimminger W., Preiss J., Hensel M., Fröhling S., Döhner K., Haas<br />
R., Döhner H.: Risk-adapted postremission therapy in acute myeloid<br />
leukemia: results of the German multicenter AML HD93<br />
treatment trial. Leukem. 17 (8) 1521-1528, 2003.<br />
[94] Schlenk R.F., Fröhling S., Benner A., Addamo B.,<br />
Hartmann F., del Valle F., Pralle H., Fischer J.T., Kölbel C.B.,<br />
Grimminger W., Mergenthaler H.G., Preiss J., Hensel M.,<br />
Glasmacher A., Peschel C., Waterhouse C., Salwender H.,<br />
Biedermann H.G., Kneba M., Kremers S., Koller E., Griesinger F.,<br />
Döhner K., Haas R.: Phase III- study of all-trans retinoic acid in<br />
previously untreated patients 61 years or older with acute myeloid<br />
leukemia: AMLSG ULM study HD98B. Onkol. 26(S5), p.1<br />
(V137), 2003.