MDCK-MRP2 - Dkfz
MDCK-MRP2 - Dkfz
MDCK-MRP2 - Dkfz
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Forschungsschwerpunkt C<br />
Krebsrisikofaktoren und Krebsprävention<br />
[40] Fröhling S., Schlenk R.F., Breitruck J., Benner A.,<br />
Kreitmeier S., Tobis K., Döhner H., Döhner K.: Prognostic significance<br />
of activating FLT3 mutations in younger adults (16 to 60<br />
years) with acute myeloid leukemia and normal cytogenetics: a<br />
study of the AML study group Ulm. Onkol. 25(S4), p.218 (769),<br />
2002.<br />
[41] Gastl G., Berdel W., Edler L., Jaehde U., Port R.E., Mross<br />
K.B., Scheulen M.E., Sindermann H., Dittrich C.: Standard operating<br />
procedures for clinical trials of the CESAR - Central European<br />
Society for Anticancer Drug Research - EWIV. Onkol. 26<br />
(Suppl.6) , 2003.<br />
[42] Geisler I., Kopp-Schneider A.: Modeling the formation<br />
and growth of radiation induced liver focal lesions. pp.68-69,<br />
2002. Freiburg, Germany, Int.Biometr.Soc. Proceedings XXIth<br />
International Biometric Conference, July 21-26.<br />
[43] Goldschmidt H., Sonneveld P., Cremer F.W., van der Holt B.,<br />
Westveer P., Breitkreutz I., Benner A., Glasmacher A., Schmidt-<br />
Wolf I.G.D., Martin H., Hölzer D., Ho A.D., Lokhorst H.M.: Joint<br />
HOVON-50/GMMG-HD3 randomized trial on the effect of thalidomide<br />
as part of a high-dose therapy regimen and as maintenance<br />
treatment for newly diagnosed myeloma patients. Ann.Hemtol.<br />
82 654-659, 2003.<br />
[44] Görner M., Weber-Nordt R., Höpfner S., Benner A., Luft<br />
T., Ho A.D.: Addition of a low fixed number of CD3+ cells to<br />
CD34-enriched allografts: effects on engraftment, graft-versushost<br />
disease, and survival after related und unrelated peripheral<br />
stem cell transplantation. J.Hematother.Stem Cell Res. 12 (3)<br />
309-320, 2003.<br />
[45] Hamann U., Liu X., Lange S., Ulmer H.U., Benner A., Scott<br />
R.J.: Contribution of BRCA2 germline mutations to hereditary<br />
breast/ovarian cancer in Germany. J.Med.Genet. 39 (3) E12,<br />
2002.<br />
[46] Hauer K., Hildebrandt W., Sehl Y., Edler L., Oster P., Dröge<br />
W.: Improvement in muscular performance and decrease in tumor<br />
necrosis factor level in old age after antioxidant treatment.<br />
J.Mol.Med. 81 (2) 118-125, 2003.<br />
[47] Heinzl H., Edler L.: Assessing uncertainty in a toxicokinetic<br />
model for human lifetime exposure to TCDD.<br />
Organohalogen Comp. 59 355-358, 2002.<br />
[48] Heinzl H., Edler L.: Evaluating and assessing uncertainty<br />
of large-scaled statistical analyses exemplified at the Boehringer<br />
TCDD cohort. Paper #52, pp.87-94, 2003. Amsterdam, Netherlands,<br />
Inst.Res.Extramural Med., VU Univ. Proc. of the 2nd<br />
Workshop on Research Methodoloy http://www.knaw.nl/<br />
rm2003/<br />
[49] Hofheinz R., Hartung G., Samel S., Hochhaus A., Hehlmann<br />
R., Pilz L., Queisser W.: Second-line treatment of advanced<br />
colorectal cancer with irinotecan, 24-hour high-dose 5-fluorouracil<br />
(HD-5-FU) and folinic acid (FA) after failure for HD-5-FU/FA.<br />
J.Cancer Res.Clin.Oncol. 128(Suppl.1), p.80 (P408), 2002.<br />
[50] Hofheinz R.D., Wenz F., Willecke F., Post S., Edler L.,<br />
Hartung G., Hochhaus A.: Randomized phase III study of adjuvant<br />
radiochemotherapy with Capecitabine versus 5-Fluorouracil<br />
(5-FU) in rectal carcinoma. Onkol. 25(6), p.593, 2002.<br />
[51] Hofmann U., Szedlak M., Rittgen W., Jung E.G.,<br />
Schadendorf D.: Primary staging and follow-up in melanoma patients<br />
- monocenter evaluation of methods, costs and patient<br />
survival. Brit.J.Cancer 87 (2) 151-157, 2002.<br />
[52] Höpfner S., Görner M., Benner A., Henning P., Ho A.D.:<br />
Unrelated donor transplantation after reduced intensity conditioning<br />
as an approach for patients lacking related donors for allogeneic<br />
stem cell transplantation. J.Hematother.Stem Cell Res.<br />
12 (3) 331-339, 2003.<br />
[53] Höpfner S., Görner M., Benner A., Ho A.D.: Nonmyeloablative<br />
transplantation - comparison of related versus unrelated<br />
donors. Onkol. 25(S4), p.97 (336), 2002.<br />
C060<br />
Biostatistik<br />
[54] Ittrich C., Deml E., Österle D., Küttler K., Mellert W.,<br />
Brendler-Schwaab S., Enzmann H., Schladt L., Bannasch P.,<br />
Härtel T., Mönnikes O., Schwarz M., Kopp-Schneider A.:<br />
Prevalidation of a rat liver foci bioassay (RLFB) based on results<br />
from 1600 rats: a study report. Toxicol.Pathol. 31 (1) 60-79,<br />
2003.<br />
[55] Kienle D., Kröber A., Katzenberger T., Otto G., Leupolt E.,<br />
Barth T., Möller P., Benner A., Habermann A., Müller-Hermelink<br />
H.K., Bentz M., Lichter P., Döhner H., Stilgenbauer S.: VH mutation<br />
status and VDJ rearrangement structure in mantle cell lymphoma:<br />
correlation with genomic aberrations, clinical characteristics<br />
and outcome. Onkol. 26(S5), p.162 (P825), 2003.<br />
[56] Kienle D., Kröber A., Katzenberger T., Otto G., Leupolt E.,<br />
Barth T.F.E., Möller P., Benner A., Habermann A., Müller-<br />
Hermelink H.K., Bentz M., Lichter P., Döhner H., Stilgenbauer S.:<br />
VH mutation status and VDJ rearrangement structure in mantle<br />
cell lymphoma: correlation with genomic aberrations, clinical characteristics,<br />
and outcome. Blood 102 (8) 3003-3009, 2003.<br />
[57] Kienle P., Buhl K., Kuntz C., Dux M., Hartmann C., Benner<br />
A., Herfarth C., Lehnert T.: Prospective comparison of endoscopy,<br />
endosonography and computed tomography for staging of<br />
tumours of the oesophagus and gastric cardia. Digestion 66 (4)<br />
230-236, 2002.<br />
[58] Kienle P., Koch M., Autschbach F., Benner A., Treiber M.,<br />
Wannenmacher M., v.Knebel-Doeberitz M., Buchler M., Herfarth<br />
C., Weitz J.: Decreased detection rate of disseminated tumor<br />
cells of rectal cancer patients after preoperative chemoradiation:<br />
a first step towards a molecular surrogate marker for neoadjuvant<br />
treatment in colorectal cancer. Ann.Surg. 238 (3) 324-<br />
331, 2003.<br />
[59] Kienle P., Weitz J., Benner A., Herfarth C., Schmidt J.:<br />
Laparoscopically assisted colectomy and ileoanal pouch procedure<br />
with and without protective ileostomy. Surg.Endosc. 17 (5)<br />
716-720, 2003.<br />
[60] Kienle P., Weitz J., Koch M., Benner A., Herfarth C.,<br />
Schmidt J.: Biofeedback versus electrostimulation in treatment of<br />
anal sphincter insufficiency. Digest.Dis.Sci. 48 (8) 1607-1613,<br />
2003.<br />
[61] Kim B.S., Park J.J., Edler L., Fournier D.v., Haase W.,<br />
Sautter-Bihl M.L., Gotzes F., Thielmann H.W.: The second derivative<br />
of the dose-time-response surface as a measure of DNA repair<br />
kinetics in the comet assay. Environmetrics 14 169-182,<br />
2003.<br />
[62] Kim B.S., Park J.J., Edler L., v.Fournier D., Haase W.,<br />
Sautter-Bihl M.L., Gotzes F., Thielmann H.W.: New measure of<br />
DNA repair in the single-cell gel electrophoresis (Comet) assay.<br />
Environ.Mol.Mutagen. 40 50-56, 2002.<br />
[63] Kinscherf R., Cafaltzis K., Röder F., Hildebrandt W., Edler<br />
L., Deigner H.P., Breitkreutz R., Feussner G., Kreuzer J., Werle<br />
E., Michel G., Metz J., Dröge W.: Cholesterol levels linked to abnormal<br />
plasma thiol concentrations and thiol/disulfide redox status<br />
in hyperlipidemic subjects. Free Radic.Bio.Med. 35 (10) 1286-<br />
1292, 2003.<br />
[64] Klaes R., Benner A., Friedrich T., Ridder R., Herrington S.,<br />
Jenkins D., Kurman R.J., Schmidt D., Stoler M., Knebel-Doeberitz<br />
M.v.: p16INK4a immunohistochemistry improves interobserver<br />
agreement in the diagnosis of cervical intraepithelial neoplasia.<br />
Am.J.Surg.Pathol. 26 (11) 1389-1399, 2002.<br />
[65] Kopp-Schneider A.: Mechanistic carcinogenesis models in<br />
quantitative risk assessment: potentials and limitations. pp.5-6,<br />
2002. Freiburg, Germany, Int.Biometr.Soc. Proceedings XXIth<br />
International Biometric Conference, July 21-26.<br />
[66] Kopp-Schneider A., Geisler I., Edler L.: Complex<br />
mechanistic carcinogenicity modeling. In: Endocrine disrupters<br />
and carcinogenic risk assessment. IOS Press, 2002, pp.317-328.<br />
[67] Korshunov A., Neben K., Wrobel G., Tews B., Benner A.,<br />
Hahn M., Golanov A., Lichter P.: Gene expression patterns in<br />
ependymomas correlate with tumor location, grade, and patient<br />
age. Am.J.Pathol. 163 (5) 1721-1727, 2003.<br />
DKFZ 2004: Wissenschaftlicher Ergebnisbericht 2002 - 2003<br />
213