MDCK-MRP2 - Dkfz

Forschungsschwerpunkt B
Funktionelle und Strukturelle Genomforschung
[15] J. Wiemer, F. Schubert, M..Granzow, T. Ragg, J. Fieres, J.
Mattes, R. Eils (2003) Informatics United: exemplary studies
combining medical informatics, neuroinformatics and
bioinformatics. Methods Inf Med. 42:126-33.
[16] F. Schubert, J. Müller, B. Fritz, P. Lichter, R. Eils (2003) Understanding
the Classication of Tumors with a Support Vector Machine:
A Case-Based Explanation Scheme. Proceedings of the
German Conference on Bioinformatics 2003, Garching, Oct 12-
14, 2003. pp. 123-127.
[17] O. Schmidt-Kittler, T. Ragg, A. Daskalakis, M. Granzow, A.
Ahr, T.J.F. Blankenstein, M. Kaufmann, J. Diebold, H. Arnholdt, P.
Müller, J. Bischoff, D. Harich, G. Schlimok, G. Riethmüller, R. Eils,
and C.A. Klein (2003). From latent disseminated cells to overt
metastasis: Genetic analysis of systemic breast cancer progression.
Proc. Natl. Acad. Sci USA, 100:7737-42.
[18] J. Gotter, B. Brors, M. Hergenhahn and B. Kyewski . Medullary
epithelial cells of the human thymus express a highly diverse
selection of tissue-specific genes colocalized in chromosomal clusters.
J. Exp. Med. 199:155-166.
[19] R. König and R. Eils (2004) Gene expression analysis on
biochemical networks with the potts spin model. Bioinformatics, in
press.
[20] S. Bulashevska, O. Szakacs, B. Brors, R. Eils and G. Kovacs
(2004) Pathways of urothelial cancer progression suggested by
Bayesian network analysis of allelotyping data. Int. J. Cancer, in
press.
[21] R. König, D. Baldessari, N. Pollet, C. Niehrs and R. Eils
(2004). Reliability of gene expression ratios for cDNA
microarrays in multi-conditional experiments with a reference design,
Nucleic Acids Res., 32, e29.
Patente
[22] R. Eils, P. Lichter, T. Ragg et al. (2002) An Expert System
for Clinical Outcome Prediction. European Patent pending.
Europäische Patentanmeldung 02 01 7411.6
[23] B. Brors, N. Hauser, M. Vingron (2002) Method and system
for determining absolute mRNA quantities (WO03083127).
Europäische Patentanmeldung EP 2002 00 07 267
Internationale Patentanmeldung WO 2003 EP 03291 2003 0328
[24] R. Eils, B. Brors, T. Haferlach, C. Schoch, S. Schnittger, S.
Mergenthaler, A. Kohlmann, W. Kern, M. Dugas (2002) Novel Genetic
Markers for Leukemias (WO03039443).
Europäische Patentanmeldung 2001 01 126 244.1
Internationale Patentanmeldung WO 2002 EP 12303 2002 1104
Dissertationen:
[25] D. Gerlich (2002) Dynamics of nuclear architecture investigated
by live cell microscopy and quantitative 4D reconstruction.
Dissertation, Universität Heidelberg.
[26] C. Athale (2003) Modelling Nuclear Body Dynamics in Living
Cell by 4-D Microscopy, Image Analysis and Simulation. Dissertation,
Universität Heidelberg.
Abteilung B080
Theoretische Bioinformatik
DKFZ 2004: Wissenschaftlicher Ergebnisbericht 2002 - 2003
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