Abstracts Book - IMRC 2018

• SB6-O017 Invited Talk
HIGH PERFORMANCE POLYMERIC AND METALLIC IMPLANT
MATERIALS
Laszlo Sajti 1 , Jelena Horky 1 , Maciej Krystian 1 , Bernhard Mingler 1 , Manfred Bammer 1
1 AIT Austrian Institute of Technology, Biomedical Systems, Austria.
We address a broad overview of recent technological developments of various
implant materials for a broad range of human applications covering both
metallic and polymeric implant designs. In the field of metallic implants, we
present equal channel angular pressing (ECAP) of low-alloyed magnesium, such
as titanium and titanium alloys mainly for trauma, craniomaxillofacial and
orthopedic implantology. In case of magnesium, we aim to reach a desired
combination of high biocompatibility, tailored mechanical and degradation
properties as well as excellent material characteristics (in particular high
strength for load bearing applications). All these requirements were achieved
using small amounts (< 1 wt.%) of alloying elements such as zinc and calcium
during the alloy production and the subsequent material optimization by ECAP.
In the processed Mg-alloys unprecedented high strength values of up to 400
MPa were achieved comparable to permanent implant materials like pure
titanium (CP-Ti) and surgical steel. For permanent implant designs CP-Ti is a
commonly used material, especially in oral/dental surgery. In this application
area, the use of titanium alloys such as Ti6Al4V-ELI is often limited to avoid
problematic alloying elements such as aluminum and vanadium. For CP-Ti
processed with ECAP, an ultimate tensile strength > 900 MPa was realized,
reaching the characteristics of Ti6Al4V-ELI, with maintaining high ductility of >
20% having homogeneous ultrafine grain structure across the entire
workpiece. We equally address the importance of implant-organ and implantcell
interfaces, with the aim of developing tailored implant surfaces that support
a high degree of cellular acceptance and biocompatibility. In this context, we
present nanotechnology-enhanced implant materials providing long-term
antibacterial, antithrombotic and for bone-anchoring applications, osseointegrative
behavior. These novel implant materials act as bioactive platforms
towards “ideal implants” with combined properties supporting an efficient tissue
regeneration. These nano-additives are based on laser-generated ultra-pure
nanoparticles, allowing specific cellular actions for both full-embedding into
polymeric matrices or used as implant coatings. Finally, we report on the
detailed mechanical, corrosive and biological characteristics of these novel
materials providing deep insights into their biophysical performance, durability,