Abstracts Book - IMRC 2018

• SB6-O020
NANOTHERMOMETRY BASED ON NANODIAMONDS IN
COLLOIDAL SOLUTION
Karla Santacruz Gomez 1 , Juan Ramirez 2 , Monica Acosta Elias 2 , Marcelino Barboza Flores 2 ,
Rodrigo Melendrez Amavizca 2 , José García Solé 3 , Martin Pedroza Montero 2 , Eduardo Montes
Ramirez 3
1 Universidad de Sonora, Physics Department, Mexico. 2 Universidad de Sonora, Department of
Physics Research, Mexico. 3 Universidad Autónoma de Madrid, Material Physics Department,
Spain.
Hyperthermia therapy based on nanostructured systems, including metallic or
magnetic nanoparticles as nanoheaters, represent a breakthrough for
therapeutic strategies against cancer. It consist in increasing local temperatura
(41-45 °C) of a tumour to annihilate cancer cells. In this sense, precise localized
sensing of temperature is determining to control and improve such
therapies. Nanodiamonds (NDs) exhibit remarkable mechanical and optical
properties, high surface areas and easy surface functionalization. They also nontoxic
and biocompatible which makes them suitable for biomedical applications
in drug delivery, bioimaging and tissue engineering. They also containg higly
luminescent Nitrogen vacancies (NV) defects making them useful as fluorescent
agents. Here, we use the intensity of photoluminescence of NV- centers in NDs
to sense temperature. These NDs sensors are dispersed in aqueous solution
and are colloidably stable. Both features good precision and colloidal stability
allow the measurements of temperatura in biological enviroments.
Keywords: hyperthermia therapy, nanodiamonds, nanothermometry
Presenting authors email: karla.santacruz@unison.mx