Abstracts Book - IMRC 2018

• SB6-P095
MICROWAVE-ASSISTED SYNTHESIS OF AMINOBORONIC-
FUNCTIONALIZED CARBON DOTS AND ITS APPLICATION AS A
GLUCOSE ON-OFF SENSOR
Hector Daniel Ibarra Prieto 1 , Ignacio Alfredo Rivero Espejel 1
1 Instituto Tecnológico de Tijuana, Centro de Graduados e Investigación en Química, Mexico.
Carbon dots (C-dots) has been considered as potential candidates for
therapeutic and diagnostic applications mainly because of its physicochemical
properties such as its solubility on water, a tunable gap band luminescent
activity, photostability, biocompatibility and low cytotoxicity.
One of those applications is as a recognition probe in chemosensors, due to
their good fluorescence activity. Xia and co-workers proved in 2014 a one-pot
synthesis route to form boronic acid-functionalized C-dots. These boronic acids
on the C-dot surface have good interaction with 1-3 diols, such as glucose,
fructose and galactose, resulting in a lineal fluorescence quenching of the C-dot.
This synthesis route was performed via hydrothermal process at 160 ºC for 8 h.
Our work group developed a variation of the Xia’s one-pot route via microwaveassisted
synthesis for C-dots, utilizing 3-aminophenyl boronic acid as precursor
(7 min, 160 ºC, 100W). A titration with carbohydrates was performed, and we
found that there is a linear quenching of fluorescence with fructose and
galactose of the C-dots, but in presence of glucose there is an enhancement of
this property. Herein, we propose the aminoboronic-functionalized C-dots as
viable, low-cost option of on-off sensor for glucose.
Acknowledgment:
We would like to thank CONACYT for their finacial support in the realization of
this project.
Keywords: Carbon dots, Microwave-assisted synthesis, Fluorescent sensor
Presenting authors email: leipd.2@gmail.com