Abstracts Book - IMRC 2018

• SB6-P040
ELECTROSPINNING TECHNIQUE USED FOR THE FABRICATION OF
FIBROUS TUBES MADE OF PLA-GELATIN WITH POSSIBLE
APPLICATION IN BLOOD VESSEL TISSUE ENGINEERING
Abraham Alejandro Leyva Verduzco 1 , María Mónica Castillo Ortega 1
1 Universidad de Sonora, Departamento de Investigación en Polimeros y Materiales, Mexico.
Cardiovascular diseases cause certain health problems and in order to solve
them an invasive procedure known as artery bypass is used. In this intervention
the blood flow is reflected using a vascular graft a healthy place to a place where
the blood is not nourishing the tissue due to an occlusion for example, in the
coronary artery bypass surgery an autograft is commonly use, this autograft
could be the saphenous vein or the internal mammary artery. However some
scientists have proposed to replace the autograft with a cylinder made of a
biocompatible plastic material or use the concept of tissue engineering where a
biocompatible and biodegradable scaffold with the shape of the graft performs
the function of the artery and also serves as a physical medium where cells can
attatch, proliferate, differenciate and excrete the components of extracellular
matrix that are required to create new tissue. In the present work two composite
materials made poly lactic acid and gelatin were fabricated by electrospinning
technique. The fabrication process and thermal (TGA, DSC), spectroscopic (FTIR),
mechanical and microscopic(SEM) characterization is presented to compare a
blended and a core-shell structures as blood vessel tissue scaffolds
Keywords: Electrospinning, tissue engineering, PLA
Presenting authors email: abrahamaalv@hotmail.com