Abstracts Book - IMRC 2018

• SB6-P106
COMPARATIVE EFFECTS ON RAT PRIMARY ASTROCYTES AND C6
RAT GLIOMA CELLS CULTURES AFTER 24 HOURS EXPOSURE TO
SILVER NANOPARTICLES (AgNPs)
Samuel Salazar 1
1 Universidad Autónoma de San Luis Potosí, Ciencias Químicas, Mexico.
Glioblastoma multiforme (GBM) is one of the most aggressive primary brain
tumor and current treatments lead to diverse side-effects; for this reason is
imperative to investigate new approaches, including those alternatives provided
by nanotechnology, like nanomaterials (NMs) such as silver nanoparticles. The
aim of this work was to compare the effects of 24 hours exposure of rat primary
astrocytes and C6 rat glioma cells to per se, can confer differential biological
effects because of the nano scale. In summary, this work constitutes for the first
time a comparative study between C6 rat glioma cells and primary astrocytes
employing the same type of AgNPs, emphasizing the contrast between normal
and pathological conditions, and provides new perspectives that could
contribute in the development of new tools or alternatives based on
nanotechnology, contributing in the understanding, impact and use of NMs in
targets like glioblastoma.
Keywords: Silver nanoparticles, glioma, primary astrocytes
Presenting authors email: samuelsg_9@hotmail.comU