Abstracts Book - IMRC 2018

• SB2-P045
EFFECT OF ZINC OXIDE NANOPARTICLES IN A NATURAL
OINTMENT
Esteban Alberto González García 1 , Zayra Melissa San Juan Refugio 2 , Olda Alexia Cardenas
Cortez 3 , Dinorah Diaz del Angel 2 , Hada Aurora Hernandez Valdez 2 , Iris Sabday Papayanopulos
Ruiz 2 , Luis Medina Torres 4
1 Instituto Tecnologico Superior de Poza Rica, Ingeniería en Gestión Empresarial, Mexico.
2 Instituto Tecnologico Superior de Poza Rica, Ingeniería en Nanotecnología, Mexico. 3 Instituto
Tecnologico Superior de Poza Rica, Ingeniería en Nanotecnogía, Mexico. 4 Universidad Nacional
Autónoma de México, Farmacia, Mexico.
In this work the development of a natural ointment added with Zinc oxide
nanoparticles (ZnO) and Hamelia Patens extract is presented, with the aim of
achieving healing on first degree burns, as well as skin protection against ultraviolet
rays. The process consists of 4 stages that will later be described chronologically. In
the first stage, the photochemical extraction by the Soxhlet method is mentioned,
a minimum of twelve hours were required for its preparation, the longer the
mixture remained in the soxhlet the more pure compounds were obtained. In the
second stage of the ointment’s synthesis process zinc oxide nanoparticles (ZnO)
were obtained, which were stabilized to have greater control in terms of size and
morphology; during this process different precursors, reducers and stabilizers were
chosen. The selected nanoparticles were the ones that showed the highest
reflection of the ultraviolet light spectrum and an adequate size between 12-38 nm.
The third stage was the preparation of the base ointment from natural agents, the
process consisted of placing beeswax and cocoa butter in bain marie, then the
dissolution lanolin and almond oil were incorporated and finally, an essence of
roses was added. The fourth stage consisted of adding the previously obtained
products to the base cream. Different prototypes were created in order to study the
concentration, factors such as temperature and time of agitation of the
nanoparticles synthesis were also considered. In the characterization of zinc oxide
nanoparticles (ZnO), morphology techniques such as UV-visible Spectrophotometry
and the Transmission Electron Microscopy (TEM) were required. The former to
know the absorption of the ultraviolet light spectrum and the latter to determine
the size and shape of the nanoparticles. Furthermore, rheometry was included as a
mechanical technique, in order to determine the ointment’s viscoelastic properties.
Keywords: oinment, nanoparticles, Hamelia Patens
Presenting authors email: melissa_0097@hotmail.com