Abstracts Book - IMRC 2018

• SB6-P080
SYNTHESIS OF OLIGOMER D-A-D BASED ON DPP WITH POTENTIAL
BIOMEDICAL APPLICATION
Oscar Javier Hernández Ortiz 1 , María Isabel Reyes Valderrama 1 , Rosa Angeles Vazquez 1 , Mario
Alejandro Rodríguez Rivera 2
1 Universidad Autónoma del Estado de Hidalgo, Área Acádemica de Ciencias de la Tierra y
Materiales, Mexico. 2 Centro de Investigaciones en Optica, Grupo de Propiedades Ópticas de la
Materia, Mexico.
In recent years, organic nanoparticles (ONPs) with pi-conjugated systems have
received widespread attention in the biomedical fields. One of the most
interesting and useful optical properties of these pi-conjugated systems is the
two photon absorption (TPA, Two photon absortion), which has allowed the use
of this type of compounds in photonic and biological applications such as
biosensors, Two-photon absorption microscopy and dynamic phototherapy. In
the last case it is essential that the compounds emit energy that allows the
generation of singlet oxygen and in this way promote the death of cancer cells.
In this paper we present the theoretical DFT study of three molecules with
quadrupolar electronic architecture based on the acceptor diketopyrropyrrole
fragment (DPP), coupled to different quinolinic and triphenylamino groups by a
π-conjugated thiophene bridge. As well as the synthesis of the most promising
of the oligomers studied theoretically, chemical and optical characterization is
presented. This oligomer derived DPP with quadrupole electronic architecture
is proposed for its potential biomedical application as singlet oxygen generator.
Keywords: DPP, Singlet oxygen, Oligomer
Presenting authors email: ojavier.hdez@gmail.com