Abstracts Book - IMRC 2018

• SB3-O010
EFFECT OF BIOGLASS 45S5 AS A CERAMIC REINFORCEMENT IN
POROUS SCAFFOLDS OF POLYLACTIC ACID MANUFACTURED BY
SEPARATION OF PHASES
Joaquin Villalba Guevara 1 , Ena Athenea Aguilar Reyes 1 , Carlos Alberto Leon Pati�o 1
1 Universidad Michoacana de San Nicolás de Hidalgo, Instituto de investigación en Metalurgia y
Materiales, Mexico.
The Bioglass 45S5 has taken great importance in the biomedical area due to its
biocompatibility, also this material is an important precursor for the formation
of hydroxyapatite, which is an inorganic material present in teeth and bones.
Adding a ceramic as a second phase to the polymeric matrix improve the
mechanical properties, and if such second phase presents biocompatibility can
enhance its bioactive performance. The objective of this study is to analyze the
effect of Bioglass 45S5 content on the morphology and crystallinity of porous
scaffolds. Porous scaffolds were prepared with polylactic acid and reinforced
with 5, 10 and 15% of Bioglass 45S5 powder, with an average particle size of 14
μm using the solvent and temperature-induced phase separation method
(NTIPS). For this, dichloromethane and hexane were employed as solvent and
non-solvent, respectively, and refrigerated at -20 °C. In order to know the
crystallization temperature of the precursor materials, a differential scanning
calorimetry test was carried out. Values of 113°C and 678°C were found for
polylactic acid and bioglass 45S5, respectively. This technique was also used to
determine the crystallinity of the scaffolds obtaining percentages of around
50%. The characterization of scaffolds by scanning electron microscopy
indicated that the pore size is in the range of 20 to 100 μm with interconnected
porosity. Thus, this method allows the preparation of scaffolds with the
microstructure, porosity and pore size in the adequate range to sustain
adhesion and cell growth.
Keywords: Scaffolds, Bioglass, Polylactic acid
Presenting authors email: j.vg7@hotmail.com