Abstracts Book - IMRC 2018

• SB2-P046
STUDY OF THE HYDROXYAPATITE PARTICLE MORPHOLOGY FROM
THE SOL-GEL TECHNIQUE, VARYING ITS SYNTHESIS CONDITIONS
Tannia Rosa Yolanda Sandoval Arriaga 1 , Isaac Muñoz Juárez 2 , María Cristina Piña Barba 3 , Juan
Manuel Perez Osorio 3
1
Instituto de Investigaciones en Materiales, Metálicos y Cerámicos, Mexico. 2 Centro de
Investigación e Innovación Tecnológica, Posgrado, Mexico. 3 Universidad Nacional Autónoma de
México, Metálicos y cerámicos, Mexico.
Biomaterials are compounds with properties that make it possible to interact
with biological systems and are designed to replace human tissues, so that they
can recover or obtain the function of them without affecting the health of the
patient. A promising biomaterial is hydroxyapatite (HA), which is an inorganic
compound that is naturally present in the bones of humans and animals in a
high percentage (65%). The synthetic HA presents an excellent biocompatibility
and osseointegration, for which one of its main uses has been bone
reconstruction. This one has the capacity to unite with the bone directly, and its
mechanism of bone induction is influenced by factors such as microporosity,
geometry, topography and surface area; therefore designing a bone filling that
takes into account these factors and study the cellular population behavior
becomes of paramount importance [1]. Depending on the synthesis method,
different properties are obtained in HA and it has been found that by controlling
parameters such as pH, mixing temperature, reaction time, treatment
atmosphere, among others [2,3], it is possible to control its degree of
crystallinity, morphology, crystal size and phase composition. There are a variety
of methods to achieve the synthesis of HA, some examples are hydrothermal
methods, precipitate, solid state techniques among others. In the present work
was synthesized HA by the sol-gel method, using as precursors phosphorus
pentoxide , calcium nitrate tetrahydrate , paying special attention to the mixing
temperature, conditions of humidity and time of calcination; the samples were
characterized with SEM to observe how these variables influence their
morphology and XRD was be used to indicate phase composition and
crystallinity.
References
[1] S. Kattimani, K.P. Lingamaneni KondakaHydroxyapatite - Past, Present, and
Future in Bone Regeneration, Bone and Tissue Regeneration Insights (2016), 9-