Abstracts Book - IMRC 2018

• SB6-P101
NANOCOMPOSITE OF GRAPHENE OXIDE COULPED WITH
HOLLOW GOLD NANOSHELLS FOR ENHANCENMENT OF
PHOTOTHERMAL APPLICATIONS
Sayma Adriana Rodriguez Montelongo 1 , Facundo Ruiz 1 , Omar González 2 , Sonia Silva Ramirez 2 ,
Samuel Kolosovas 3
1 Universidad Autónoma de San Luis Potosí, Facultad de Ciencias, Mexico. 2 Universidad
Autónoma de San Luis Potosí, Facultad de Ciencias Quimicas, Mexico. 3 Universidad Autónoma
de San Luis Potosí, Ciacyt, Mexico.
Graphene due to its unique properties, the biocompatibility that presents and
easy functionalization has gained a great interest in the field of biomedicine.
Specifically, several studies have focused on the photothermal capacity
exhibited by graphene oxide (GO) and its reduced form (rGO), which surface is
intended to be linkeaged with hollow gold nanoshells (HGN) that present the
phenomenon of surface plasmon resonance (SPR) and which is adjustable to
various dimensions. HGNs have the ability to absorb or disperse light at
wavelengths from the visible to the near infrared (NIR), especially in the 650 to
1300 nm range where there is minimal absorption of the tissue components and
the absorbed light is transformed into heat resulting in the photothermal
ablation of tumor cells. Therefore, the propose of this project is development a
nanocomposite based on the combination of these materials in order to
increase the photothermal effect and be potentially useful as therapeutic agents
against cancer. As preliminary results, cytotoxicity assays were performed on
two cell lines exposed to the HGN for 24 hr, as well as photothermal effect of
graphene samples and HGN irradiated with an 810 nm laser where a
temperature increase proportional to the concentration was observed.
Keywords: nanocomposite, nanoshells, graphene-oxide
Presenting authors email: sym_adra@hotmail.com