Abstracts Book - IMRC 2018

• SB6-O024 Invited Talk
POLYMER BIOMATERIAL SURFACE MODIFICATION: THE KEY TO
INTEGRATION
Marta Cerruti 1
1 McGill University, Materials Engineering, Canada.
Polymeric materials are used in many biomedical applications due to their
biocompatibility; they range from biodegradable polyesters such as poly-D, L-
lactic acid (PDLLA) used in sutures to inert stiff polymers like poly-ether-ether
ketone (PEEK) for orthopedic applications. Despite their good biocompatibilty,
most polymers are hydrophobic and do not have functionalities that promote
adherence of the desired proteins and cells, or the nucleation and growth of
hydroxyapatite if they are to be used in hard tissue regeneration.
In this talk we will explore how we can modify the surface of polymeric
biomaterials including PDLLA, PEEK and polystyrene to improve their bioactivity
and integration with cells and tissues. We will focus on osteointegration and
immune response, showing that different functional groups can enhance
biomineralization and/or pro or anti-inflammatory response of macrophages.
Acknowledgment:
Natural Sciences and Engineering Reserach Council of Canada
Canada Research Chair Foundation
Keywords: Biomaterial, Surface, Polymers
Presenting authors email: marta.cerruti@gmail.com