Abstracts Book - IMRC 2018

• SB2-P052
POLYMER-NANOSTRUCTURED CARBON CAPSULES EFFECTS IN
MDA-MB-231 CANCER CELLS
Santos Adriana Martel Estrada 1 , Claudia-Lucía Vargas Requena 2 , Elí Santos Rodríguez 3 , Dulce
Azucena Salazar Vázquez 4 , Karen Andrea Legarreta Arias 4 , José Emmanuel Sánchez Serrano 4 ,
Carlos Alberto Martínez Pérez 5 , Laura Valencia Gómez 5 , Lorena Rivera Rios 5
1 Universidad Autónoma de Ciudad Juárez, Diseño, Mexico. 2 Universidad Autónoma de Ciudad
Juárez, Ciencia Básicas, Mexico. 3 Universidad Autónoma de Chiapas, Centro Mesoamericano de
Física Teórica, Mexico. 4 Universidad Autónoma de Ciudad Juárez, Ciencias Básicas, Mexico.
5
Universidad Autónoma de Ciudad Juárez, Física y Matemáticas, Mexico.
Breast cancer is the most common malignancy and second important cause of
dead among woman. Mimosa tenuiflora is rich in arabinogalactans, saponins
and triperpenoid glycosides. Recently, arabinogalactans has reached interest of
scientific community due to its potential to reduce cell proliferation and to block
metastasis of liver tumor cells. Nanodiamonds are nontoxic nanoparticles for
drug delivery that may enhance effects of treatments on cancer cells. For these
reasons, in this work nanodiamonds and extract of Mimosa Tenuiflora were
encapsulated by chitosan. The properties of the particles were studied with
Fourier transformed infrared spectroscopy (FTIR), and X-ray diffraction (XRD).
The adherence of extract of Mimosa Tenuiflora was analyzed with a UV–Visible
spectroscopy at a wavelength of 253 nm. The thermal properties were analyzed
through TGA/DSC. Also the cytotoxicity of those capsules was evaluated using
MDA-MB-231 line cell. The test revealed that the particles might be used to treat
breast cancer.
Keywords: Nanodiamond, Chitosan, Mimosa Tenuiflora
Presenting authors email: mizul@yahoo.com