Abstracts Book - IMRC 2018

• SC7-P012
INCORPORATION OF METALLIC NANOPARTICLES ONTO METAL
ORGANIC FRAMEWORKS FOR DRUG DELIVERY APPLICATIONS
Julian Pastor Novelo Uc 1 , Manuel Alejandro Estrella Gutierrez 1 , Geonel Rodriguez Gattorno 2 ,
Gerko Oskam 2
1 Universidad Autónoma de Yucatán, Facultad de Ingeniería Química, Mexico. 2 CINVESTAV-
Mérida, Física Aplicada, Mexico.
Despite remarkable progress in our understanding of the fundamental biology
behind many diseases, we have yet to observe comparable advances in the
treatment of these diseases. Current therapeutics are limited by their
nonspecific distribution throughout the body leading to high doses, rapid
clearance, poor pharmacokinetics, and high side effects. Combining the
advantages of porosity and magnetism to fabricate a novel material with high
surface area and magnetic separability is undoubtedly of great interest for many
practical applications because the magnetism can endow the material a facile
manoeuvrability by applying an appropriate magnetic field, especially in the
separation of certain substances from multiphase complex systems. Magnetic
MOFs have been regarded as a promising material to combine the porosity,
functionality, and magnetism, and thus for the application of adsorptive
separation, targeted drug delivery and release. In this work we explore the
influence of Fe 2 O 3 and Co nanoparticles on the magnetic properties of two types
of MOFs to know if these materials are candidates for the drugs carriers.
Keywords: Metal organic frameworks, Magnetic properties, Drug carriers.
Presenting authors email: julian.novelo@hotmail.com