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Fármaco<br />

Ketamina<br />

Sedantes empleados para producir anestesia disociativa<br />

(vigilar como sedación profunda)<br />

Vía<br />

Dosis Inicio<br />

(mg/kg) (min)<br />

Duración<br />

Comentarios<br />

6 a 10:<br />

Usar sólo bajo supervisión directa de<br />

VO 30 min 30 a 45 10 a 30<br />

médicos con experiencia en la administración<br />

antes<br />

de anestésicos generales; tiene efectos<br />

IM 3 a 7 7 12 a 25<br />

analgésicos; el producto inyectable puede<br />

utilizarse por vía oral diluido en una bebida<br />

IV 0.5 a 2 1 5 a 10<br />

elegida por el paciente.<br />

Nota: para mayor información, véanse las monografías de cada fármaco.<br />

1. Committee on Drugs, Section of Anesthesiology, American Academy of Pediatrics.Guidelines for<br />

Monitoring and Management of Pediatric Patient During and After Sedation for Diagnostic and<br />

Therapeutic Procedures. Pediatrics. 1992;89:1110-5.<br />

2. Yager JY, Seshia SS. Sublingual Lorazepam in Childhood Serial Seizures. Am J Dis Chiid.<br />

1988;142(9):931-2.<br />

3. Fell D, Gough MB, Northan AA, et al. Diazepam Premedication ¡n Children. Anaesthesia.<br />

1985;40:12-7.<br />

4. Burckart GJ, White III TJ, Siegle RL, et al. Rectal Thiopentai Versus an Intramuscular Cocktail for<br />

Sedating Children Before Computer Tomography. Am J Hosp Pharm. 1980:37:222-4.<br />

5. Buriles R and Astley B. Lorazepam in Children. Br J Anaesth. 1983;55:275-9.<br />

6. Roelofse JA, van der Bijl P, Stegmann DH, el al. Preanesthetic Medicatíon With Recial Midazolam in<br />

Children Undergoing Dental Extractions. J Oral Maxíliofac Surg. 1990;48(8):79l-7.<br />

7. Wilton NC, Leigh J, Rosen DR, et al. Preanesthetic Sedation of Preschool Children Using Intranasal<br />

Midazolam. Anesthesiology. 1988;60(6):972-5.<br />

8. Elman DS, Denson JS. Preanesthetic Sedation of Children With Intramuscular Methohexital Sodium.<br />

Anesth Anaíg. 1965;44{5)-.494-3.<br />

9. Miller JR, Grayson M, Stoelting VK. Sedation With Intramuscular Methohexital Sodium. Am J<br />

Ophthalmo!. 1966;62(1):38-43.<br />

10. Drug Evaluations. AMA. 1980.

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