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Cytotoxic Activity of Etlingera triorgyalis and Globba unifolia from
Sekayu Recreational Forest, Terengganu
Nur Qistina Iwani binti Yurasbe
Supervisor: Dr. Thilahgavani Nagappan
Bachelor of Applied Science
(Biodiversity Conservation and Management)
School of Marine and Environmental Sciences
Etlingera triorgyalis and Globba unifolia are among hundreds of ginger species
from family Zingiberaceae that grows wild in forest of Malaysia. Lately, cancer
incidents are on rise where cervical cancer is found to affect women around the
world. The aim of this study is to determine the cytotoxic and apoptosis activity
of Etlingera triorgyalis and Globba unifolia extracts against HeLa cell lines
(human cervical cancer) using MTS assay and Annexin-V staining assay to
determine the apoptosis activity. The IC50 value of Etlingera triorgyalis and
Globba unifolia extract against HeLa cells is 83.18 g/ml and 43.65 g/ml,
respectively. The extracts also shown to undergo apoptosis process. Further
investigation pertaining to phytochemicals of the extracts is required to
understand more of the chemical that worked against the HeLa cell lines
inhibition.
1737 | UMT UNDERGRADUATE RESEARCH DAY 2018