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Secondary Metabolites from the Twigs of Mangrove Plant Avicennia
officinalis and Antioxidant Activity
Muhammad Isyraq Hazim Bin Mohd Amir
Supervisor: Dr. Noor Wini binti Mazlan
Co-Supervisor: Dr. Suvik A/L Assaw
Bachelor of Science (Analytical and Environmental Chemistry)
School of Marine and Environmental Science
Universiti Malaysia Terengganu
Avicennia officinalis is commonly known as “Api–Api Ludat”, a medium sized mangrove
plant growing in brackish water and widely found in sub-tropical coastal area. The
main objective of this study was to isolate the antioxidant active metabolites from the
twigs of A. officinalis collected from Kuala Selangor Nature Park, Selangor. The
antioxidant activity of A. officinalis fractions using DPPH free radical scavenging assay
showed potent activity on fraction 9 with inhibition concentration at 50 % (IC50) value
of 0.7 mg/mL. The active fractions 7-9 of A. officinalis were further isolated using
chromatographic techniques to give two pure metabolites, namely as avicenol C and
stenocarpoquinone B. Structure elucidation of the isolated secondary metabolites was
achieved using 1D and 2D-nuclear magnetic resonance (NMR) spectroscopy. It can be
concluded that the secondary metabolites isolated from the twigs of A. officinalis could
be lead compounds and further developed for pharmaceutical agents.
1944 | UMT UNDERGRADUATE RESEARCH DAY 2018