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Synthesis and Characterization of Acetylide-Thiourea Derivatives as
Volatile Organic Compounds (VOCs) Chemosensor.
Pavithran A/L Renganathan
Supervisor: Assoc. Prof Dr. Wan Mohd Khairul Bin Wan Mohamed Zin
Bachelor of Science (Chemical Sciences)
School Of Fundamental Sciences
An increase emissions of volatile organic compounds(VOCs) is now considered of
major environmental concern. Few methods that already developed in detecting VOCs
analyte which are by carbon nanotubes based materials , conductive polymeric
system, and metal oxides derivatives, needs special treatments like large
instrumentation, high operating temperature, and inert environment in order to be
operated. Therefore, thiourea derivatives are selected to be as a single molecule that
can be developed into a gas sensor due to their capacity for electronic transport
throughout molecular backbone favoured by rigid π-conjugated systems. In this study,
4-[(4-aminophenylethynyl] toluene as a precursor has been synthesized by using
Sonogashira cross-coupling reaction. Further reaction has been done to produce final
product alkoxy-substituted acetylide-thiourea. Characterization techniques using
Fourier Transform Infrared Spectrophotometer (FT-IR), Perkin-Elmer thermo
gravimetric analysis (TGA), nuclear magnetic resonance spectroscopy (NMR) and also
CHNS analysis has been done to confirm the molecular structure of the synthesized
product.
469 | U M T U N D E R G R A D U A T E R E S E A R C H D A Y 2018