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Mathematical Modelling in HIV/AIDS Infection in Human Population<br />

Nur Syahirah Afiqah Binti Safian<br />

Supervisor: Dr. Chong Nyuk Sian<br />

Bachelor of Science (Financial Mathematics)<br />

School of Informatics and Applied Mathematics<br />

HIV is a major global public health challenge and currently we have millions of people<br />

living with HIV. Thus, in this project, we would like to consider an HIV mathematical<br />

model to examine the transmission dynamics of HIV/AIDS virus in human population. The<br />

positively invariant and attracting region and the stability of the model will be analyzed.<br />

We identify there are two equilibria exist in the model, i.e., the disease-free and endemic<br />

equilibria. The stability of these two equilibria depends on the basic reproduction number<br />

R 0 : the disease free equilibrium is locally asymptotically stable if R 0 ≤ 1, whereas the<br />

endemic equilibrium achieves local asymptotic stability whenever R 0 > 1. In addition,<br />

numerical simulations will be performed to illustrate the dynamic of this model and<br />

validate our theoretical results. We find that the disease burden can be controlled by<br />

reducing the effective contact rate of the infected population.<br />

866 | UMT UNDERGRADUATE RESEARCH DAY 2018

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