merged

The Synthesis of Allylation Reactions of 1,3-Cyclohexanedione with Tin
Dichloride in Water
Siti Khadijah Binti Husin
Supervisor: Dr. Soraya Shafawati Binti Mohamad Tahier
Bachelor of Science (Chemical Sciences)
School of Fundamental Science
Cyclohexanedione is important as it is used as a precursor to treating cancer and
widely used as a skeleton in the production of herbicides. Some herbicides such as
Cycloxydim, Clethodim, Tralkoxydim, and Profoxydim are derivatives of 1,3-
cyclohexanedione. The allylation reaction between carbonyl compounds and allyl
halide is called the formation of the carbon-carbon bond. In this study, the allylation
reactions of 1,3-cyclohexanedione and allyl bromide were carried out using the SnCl2-
H2O system under stirring method for 7 to 9 days to get a monoallyl product which is
2-allyl-1,3-cyclohexanedione (C9H12O2). This study was carried out by using the
different equivalent of starting material and catalyst. The product obtained was
characterized by using UV-Vis spectroscopy and Infrared (IR) spectroscopy. This
research study has increased the yield of the final product by 50%.
457 | U M T U N D E R G R A D U A T E R E S E A R C H D A Y 2018