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Evaluating the Image of Collagen Architecture in Skin using
Fast Fourier Transform Method
Nur Nashrah Binti Hamsah
Supervisor: Dr. Shalela Binti Mohd Mahali
Bachelor of Science (Financial Mathematics)
School of Informatics and Applied Mathematics
This paper presents on how to study and observe the image of the collagen structure in
skin corresponding with a series of chronologically aged skin samples derived from model
of type 2 diabetes mellitus. Previously, many existing techniques have been developed to
analyze the structure of the collagen. However, most of the proposed techniques are not
sufficiently sensitive to detect progressive pathological changes in the dermis, such as
those seen in ageing. Therefore, in this research, we are evaluating the image of collagen
architecture formed from the picrosirius staining method in which the image of picrosirius
stained skin revealed the basket weave structure of dermal collagens qualitatively. Then,
by using this picrosirius image, we are able to perform a mathematical model to evaluate
the collagen structure through Fast Fourier Transform method. The evaluation results
show that some significant differences in collagen-related changes are found in different
aging skins.
863 | UMT UNDERGRADUATE RESEARCH DAY 2018