merged

Synthesis, Characterization and Antibacterial Studies of N2O2 Schiff Base
Ligand and Its Copper (II) Complex Modified Screen-
Nur Aina Binti Zainuddin
Supervisor: Dr. Siti Kamilah binti Che Soh
Co-Supervisor: Dr. Suvik A/L Assaw
Bachelor of Science (Analytical and Environmental Chemistry)
School of Marine and Environmental Science
Universiti Malaysia Terengganu
N2O2 Schiff base ligand and its copper(II) complex can be synthesized by condensation
reaction between primary amine, 1, 3-diaminopropane with carbonyl compound, 2-
hydroxyl- 4- methylacetophenone using 1:2 molar ratio. The copper(II) complex was
then obtained by complexation of copper(II) acetate with the synthesized ligand (L)
to form corresponding copper(II) Schiff base complex (CuL). The ligand and its
copper(II) complex were characterized by using different physiochemical studies such
as CHN elemental analyses, FT-IR spectroscopic, 13 C and 1 H NMR spectra, as well as
UV-vis spectra. The synthesized compounds have been subjected to antibacterial
study. The antibacterial results indicates that the antibacterial activity of Schiff base
ligand and it copper(II) complex were effectively against Gram-negative and Grampositive
bacteria using Kirby-Bauer and twofold dilution method. Copper(II) complex
showed more potent activities compared to free ligand due to exist of metal which
giving suitable support for developing new antibacterial agent.
1955 | UMT UNDERGRADUATE RESEARCH DAY 2018