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Mathematical Modelling of Cholestrol Concentration in Blood Circulation and Liver<br />

Shafinaz Ameera Binti Saidon<br />

Supervisor: Madam Siti Madhihah Binti Abd Malik<br />

Bachelor of Science (Financial Mathematics)<br />

School of Informatics and Applied Mathematics<br />

Cholesterol is found in the blood vessels as well in the human body cell and homeostasis plays a<br />

vital role to maintain physical in a balanced and stable state. However, due to unbalance<br />

homeostasis has led to health problems such as stroke, chest pain and heart attack which causing<br />

deaths each year. This study was conducted to investigate the model of two compartments for<br />

cholesterol transport in the bloodstream and liver in the human body. Then, the model is solved<br />

to generate the concentration of cholesterol profile. The solution is numerically solved by using<br />

Runge Kutta method. The results showed that there is a problem in the transportation of<br />

cholesterol from the liver to the bloodstream when the concentration ratio is less or equal to one<br />

or vice versa. Finally, this model can assist with the appropriate treatment strategy when the<br />

value of the parameter cholesterol transport is changed.<br />

883 | UMT UNDERGRADUATE RESEARCH DAY 2018

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