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Numerical Solution for Hydrophilic Matrix System of Drug Delivery
Nurul Iman Shuhada Binti Zulkifli
Supervisor: Dr. Shalela Binti Mohd Mahali
Bachelor of Science (Financial Mathematics)
School of Informatics and Applied Mathematics
In this paper, we are going to evaluate the mathematical model of the main transport
phenomena involved in the drug release process from hydrogel matrices. For the past
decades, hydrogels have been playing a significant role in areas such as biomedical
engineering, agriculture, etc. This have eventually lead to the numerous research on
hydrogels to know how it works for controlled drug delivery system. The traditional
delivery system is no longer relevant as it caused the uncontrolled and immediate drug
release kinetics. However, among the numerous research done, there are only a few that
can fully explain about the swelling phenomenon of hydrogel. The lack of understanding
about this particular process could lead to another problem. It is very crucial to
understand about rate and degree of hydrogel swelling. Numerical result shows that the
matrix composition dramatically changes with time, resulting in strongly time-dependent
conditions for the occurring mass transport process.
877 | UMT UNDERGRADUATE RESEARCH DAY 2018