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Study on Indole-3-Propionic Acid Imprinted Polymer via Precipitation
Polymerization with Methacrylic Acid (Maa) and Methyl Methacrylate
(Mma) As Functional Monomer
Noor Shahirah bt Abd Rahman
Supervisor: Dr Faizatul Shimal Bt Mehamod
Bachelor of Science (Chemical Sciences)
School of Fundamental Science
Molecularly imprinted polymers (MIPs) are highly crosslinked polymer which can bind
specifically to the target compound and used as biosensor. In this study, Indole-3-
propionic acid imprinted polymer (IPA-IP) was prepared by precipitation
polymerization with indole-3-propionic acid (IPA) as template, methacrylic acid (MAA)
and methyl methacrylate (MMA) as two different functional monomers and
divinylbenzene (DVB) as crosslinker. The formation of MIPs was determined as the
molar ratio of IPA-MAA-DVB of 1: 4: 20 by single factor experiment. By using Fouriertransform
infrared spectrometer (FTIR), all functional groups present in indole-3-
propionic acid imprinted polymer (IPA-IP) and non-imprinted polymer (NIP) were
detected. The beads formed obtained from scanning electron microscope (SEM) for
IPA-IP-co-MAA was homogeneous while IPA-IP-co-MMA was heterogeneous. The
pores volume of IPA-IP-co-MAA and IPA-IP-co-MMA obtained from Brunauer, Emmett
and Teller (BET) are 0.3146 cm 3 /g and 0.3334 cm 3 /g respectively. The binding study
using UV-Visible showed that IPA-IP-co-MMA has higher binding capacity than IPA-IPco-MAA.
425 | U M T U N D E R G R A D U A T E R E S E A R C H D A Y 2018