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Antibacterial Activity From Marine Sponges, Theonella Spp.<br />

Faridatul Afiqah Binti Zahari<br />

Supervisor: Dr. Jasnizat Bin Saidin<br />

Bachelor of Science (Marine Biology)<br />

School of Marine and Environmental Sciences<br />

Antibiotics resistance are one of major concern for the last decade. Recently, some of<br />

the pathogen are able to resist all or nearly all of available antibiotic. This study focus<br />

on the investigation of potential marine sponges, Theonella cylindrica and Theonella<br />

swinhoei for the antibacterial properties. Bioautography technique was used to<br />

evaluate the potential of Theonella spp. extract to inhibit the test bacteria which were<br />

Micrococcus sp., Bacillus subtilis, Escherichia coli and Klebsiella pneumonia. Result of<br />

bioautography showed that both extracts exhibit no antibacterial properties. This<br />

might be because few factors such as the sample itself does not contain any<br />

antibacterial compounds. Second, this might be due to non-optimized bioautography<br />

method such as amount of sample applied is too small and it oxidized due to<br />

environmental exposure during the test. For future study it is suggested that the<br />

optimization of this technique to be done before test will be conducted.<br />

1808 | UMT UNDERGRADUATE RESEARCH DAY 2018

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