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Effect of Passiflora Foetida Crude Extract on Blood Glucose Level and Body
Weight in Mice Enriched With High Fat and Carbohydrate Diet
Mohamad Alameen Bin Mustafa
Supervisor: Dr. Maziah Binti Ghazaly
Bachelor of Science (Biological Sciences)
School of Fundamental Science
Diabetes mellitus(DM) is characterized by hyperglycaemia in patient. It is due to the
absence or impairment of the insulin secretion by the pancreas together or
independence signalling deterioration at the cellular level. Passiflora foetida(P.foetida)
is known as a herb that cures a variety of diseases that have been applied worldwide.
The objectives of the study were to study the effects of P. foetida on blood glucose,
body weight, food and water intake in mice treated with high fat and carbohydrate
diet. The mice were divided into 3 groups: Control, DM and DM + Extract. Study shows
that, P.foetida able to decrease the blood glucose and body weight in mice following
treatment and there were no significant differences in the food and water intake of
mice. These data could provide a useful insight on discovering therapeutics
alternatives in treating diabetes in the future.
Keywords: Passiflora foetida, blood glucose, body weight, diabetes mellitus
376 | U M T U N D E R G R A D U A T E R E S E A R C H D A Y 2018