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Manual 1-400 - Comunidad de Madrid

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448<br />

A.J. Pérez Díaz, P. Rojo Conejo<br />

TABLA III. Tratamiento antibiótico empírico<br />

Edad Agente más frecuente Antibiótico<br />

0-3 meses S.aureus, SGB, BGN (E. coli) Cloxacilina + cefotaxima/gentamicina<br />

Menores <strong>de</strong> 5 años S.aureus, SBHGA, Cefuroxima (150 mg/kg/día)<br />

Kingella kingae > 2 años: cloxacilina +<br />

cefotaxima/ceftriaxona<br />

o como >5 años<br />

Mayores <strong>de</strong> 5 años S. aureus Cloxacilina (100-150 mg/kg/día) ó<br />

Cefazolina (100 mg/kg/día)<br />

Forma multifocal grave S. aureus Clindamicina (40 mg/kg/día) +<br />

Cloxacilina (150 mg/kg/día)<br />

BIBLIOGRAFÍA<br />

1. Hernán<strong>de</strong>z-Sampelayo Matos T, Zarzoso Fernán<strong>de</strong>z S, Navarro Gómez ML, Santos<br />

Sebastián MM, González Martínez F, Saavedra Lozano J. Protocolo <strong>de</strong> la AEP;<br />

Osteomielitis y artritis séptica.<br />

2. Krogstad P. Bacterial arthritis: Clinical features and diagnosis in infants and<br />

children; http://uptodate.papi.h12o.es/online/content/topic.do?topicKey=pedi_<br />

id/34051 &selectedTitle=1%7E150&source=search_result<br />

3. Krogstad P. Bacterial erthritis: Treatment and outcome in infants and children;<br />

http:// uptodate.papi.h12o.es/online/content/topic.do?topicKey=pedi_id/35431&<br />

selectedTitle=3%7E72&source=search_result<br />

4. The Royal Children´s Hospital Melbourne; Tha accutely swollen joint; Clinical<br />

practice gui<strong>de</strong>lines; http://www.rch.org.au/clinicalgui<strong>de</strong>/cpg.cfm?doc_id=5152<br />

5. Rojo P, Barrios M, Palacios A, Gómez C, Chaves F. Community-associated Staphylococcus<br />

aureus infections in children. Expert Rev Anti Infect Ther. 2010; 8: 541-54.

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